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Human sera and related serum-derived preparations are used in cell culture, immunoassays, and other laboratory research. Depending on the preparation, they may supplement culture media or serve as blocking reagents and assay controls.
A histamine H1 receptor antagonist (Ki = 1.3 nM) and mast cell stabilizer; selective for H1 receptors over H2 and H3 receptors (Kis = 987 and 2,500 nM, respectively); inhibits compound 48/80-induced degranulation of rat peritoneal mast cells at 50 and 100 μM; inhibits the PCA reaction in rats by 54.6% at 20 mg/kg; inhibits the quick phase airway response in a rat ovalbumin-induced immediate airway response model at 30 mg/kg
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A polyphenolic antioxidant that is abundant in many fruits vegetables plant bark and peels has anti-carcinogenic anti-mutagenic anti-inflammatory and organ-preserving properties blocks methylation of H3R17 by CARM1 without significantly altering histone acetylase or DNA methyltransferase activity
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A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More