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A polyphenolic antioxidant that is abundant in many fruits vegetables plant bark and peels has anti-carcinogenic anti-mutagenic anti-inflammatory and organ-preserving properties blocks methylation of H3R17 by CARM1 without significantly altering histone acetylase or DNA methyltransferase activity
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An analytical reference standard categorized as a synthetic cannabinoid has been detected in human hair samples tested for verification of drug abstinence intended for research and forensic applications
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An analytical reference standard that is structurally similar to known phytocannabinoids has been found in Cannabis intended for research and forensic applications
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Antgen purfed eggshell protens (Zrp and small amounts of zona pellucda protens) from Atlantc salmon (S salar) Host mouse clone MN2B4 CrossReactvty ( ) Atlantc salmon (S salar) (reacts prmarly wth B monomer) ranbow trout (O mykss) and Arctc char (S alpnus) Zrp Applcaton(s) WB and ELSA sotype gG1K
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A F508del-CFTR corrector increases CFTR levels in CFBE41o- bronchial epithelial cells expressing F508del-CFTR fused to HRP (EC50 0.13 UM) and the transepithelial current in primary human bronchial epithelial cells isolated from a patient with cystic fibrosis with the F508del-CFTR mutation (EC50 0.028 UM)
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A dopamine D2 receptor antagonist (Ki 0 3 nM in CHO cells expressing the rat receptor) selective for dopamine D2 over D3 receptors (Ki 9 5 nM) inhibits dipropyl dopamine-induced femoral vasodilation in dogs at 0 5-5 g/kg prevents dopamine-induced decreases in pentagastrin-induced gastric antral motility in dogs at 0 5 mg/kg inhibits apomorphine-induced emesis in dogs (ED50 0 031 mg/kg p o ) increases serum levels of prolactin in male rats
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A G protein-biased peptide agonist of GLP-1R selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R overBarrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s 0.63 and 79 nM respectively) induces insulin secretion in INS-1 832/3 cells (EC50 6.3 nM) reduces food intake and body weight increases plasma insulin levels and decreases plasma glucose HbA1c glucagon and triglyceride levels in diabetic db/db mice from 1.5-6 nmol/kg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A sesquiterpene lactone with anticancer activity inhibits the proliferation of MDA-MB-231 MDA-MB-468 and MCF-7 human breast cancer cells (IC50s 5.211 3.405 and 9.083 UM respectively after 48 hours) inhibits migration of MDA-MB-231 cells at 2.5 5 and 10 UM reduces tumor volume in an MDA-MB-231 orthotopic mouse xenograft model at 25 and 50 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More